The chief end of man is to glorify God. God is most glorified in us when we are most satisfied in him.
This is the basis of John Piper's book Desiring God and the philosophy he has chosen to term Christian Hedonism. Christian Hedonism claims that we, as Christians are to pursue pleasure- because this is pleasing to and brings glory to God. In the first chapter, Piper outlines this philosophy of Christian Hedonism. Chapter two explains how one becomes a Christian Hedonist. And then through out the book he shows how to live out being a Christian Hedonist in such basics as prayer, Scripture reading, marriage, money,missions and suffering.
I really enjoy John Piper's sermons and writings. This makes good sense to me. I believe God does want us to live a life of happiness in Him. So many Christians live a life that seems sad and dreary. They act like martyrs who want their martyrdom to be recognized. It is true that Christians will have suffering. Piper deals with this in chapter 10 especially. But, it also true that this suffering is to be chosen because we are looking for the joy that is to come. We are suffering to ultimately obtain our pleasure and God's glory.
This and many other of Piper's resources can be read and listened to free at the Desiring God website.